Pronunciation: (kal'kyu-lus),[key] —n., —pl.-liPronunciation: (-lī"),[key]-lus•es. 1. Math.a method of calculation, esp. one of several highly systematic methods of treating problems by a special system of algebraic notations, as differential or integral calculus.
2. Pathol.a stone, or concretion, formed in the gallbladder, kidneys, or other parts of the body.
3. Also called tartar.Dentistry.a hard, yellowish to brownish-black deposit on teeth formed largely through the mineralization of dead bacteria in dental plaques by the calcium salts in salivary secretions and subgingival transudates.
4. calculation: the calculus of political appeal.