Pronunciation: (kō'fak"tur),[key] —n. 1. Biochem.any of various organic or inorganic substances necessary to the function of an enzyme.
2. Math. a. a prefactor or postfactor.
b. the product of the minor of a given element of a matrix times -1 raised to the power of the sum of the indices of the row and column crossed out in forming the minor.