de•spairPronunciation: (di-spâr'), [key]
loss of hope; hopelessness.
someone or something that causes hopelessness: He is the despair of his mother.
to lose, give up, or be without hope (often fol. by of
): to despair of humanity.
to give up hope of.
Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease.