Pronunciation: (dif'ur),[key] —v.i. 1. to be unlike, dissimilar, or distinct in nature or qualities (often fol. by from): The two writers differ greatly in their perceptions of the world. Each writer's style differs from that of another. 2. to disagree in opinion, belief, etc.; be at variance; disagree (often fol. by with or from): His business partner always differs with him. 3. Obs.to dispute; quarrel.