Pronunciation: (dis-ôr'ē-ent", -ōr'-),[key] —v.t. 1. to cause to lose one's way: The strange streets disoriented him. 2. to confuse by removing or obscuring something that has guided a person, group, or culture, as customs, moral standards, etc.: Society has been disoriented by changing values. 3. Psychiatry.to cause to lose perception of time, place, or one's personal identity.