/ Dictionary / Index E Esau: Meaning and Definition of Find definitions for: E•sau Pronunciation: (ē'sô), [key] — n. a son of Isaac and Rebekah, twin brother of Jacob, to whom he sold his birthright. Gen. 25:21–25. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: esau (Thesaurus) Esarhaddon esbat Related Content Daily Word Quiz: rotund Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language