1. Biochem.a peptide hormone, produced by the hypothalamus, that stimulates the anterior lobe of the pituitary gland to secrete luteinizing hormone and follicle-stimulating hormone.
2. Pharm.a preparation of this hormone, used to treat precocious puberty, prostate cancer, male and female infertility, and female reproductive disorders. Abbr.: GnRH Also,go•nad"o•tro'pin-re•leas"ing hor"mone.