Pronunciation: (in-krim'u-nāt"),[key] —v.t.,-nat•ed, -nat•ing. 1. to accuse of or present proof of a crime or fault: He incriminated both men to the grand jury. 2. to involve in an accusation; cause to be or appear to be guilty; implicate: His testimony incriminated his friend. He feared incriminating himself if he answered. 3. to charge with responsibility for all or part of an undesirable situation, harmful effect, etc.: to incriminate cigarettes as a cause of lung cancer.