Pronunciation: (mak'yu-lu),[key] —n., —pl.-laePronunciation: (-lē").[key] 1. a spot or blotch, esp. on one's skin; macule.
2. Ophthalm. a. an opaque spot on the cornea.
b. Also calledmacula lutea,yellow spot. an irregularly oval, yellow-pigmented area on the central retina, containing color-sensitive rods and the central point of sharpest vision.