Pronunciation: (mad'um),[key] —n., —pl.mes•damesPronunciation: (mā-dam', -däm')[key]for 1;mad•amsfor 2, 3. 1. (often cap.) a polite term of address to a woman, originally used only to a woman of rank or authority: Madam President; May I help you, madam? 2. the woman in charge of a household: Is the madam at home? 3. the woman in charge of a house of prostitution.