Pronunciation: (reg'yu-lāt"),[key] —v.t.,-lat•ed, -lat•ing. 1. to control or direct by a rule, principle, method, etc.: to regulate household expenses. 2. to adjust to some standard or requirement, as amount, degree, etc.: to regulate the temperature. 3. to adjust so as to ensure accuracy of operation: to regulate a watch. 4. to put in good order: to regulate the digestion.