/ Dictionary / Index S Santa Ana: Meaning and Definition of Find definitions for: San•ta An•a Pronunciation: (san'tu an'u or, for 2, 4, Sp. sän'tä ä'nä), [key] a city in SW California. 203,713. a city in NW El Salvador. 174,546. (in southern California) a weather condition in which strong, hot, dust-bearing winds descend to the Pacific coast around Los Angeles from inland desert regions. See Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Santa Santa Anna Related Content Daily Word Quiz: nefarious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language