/ Dictionary / Index S Santa Barbara: Meaning and Definition of Find definitions for: San•ta Bar•ba•ra Pronunciation: (san'tu bär'bur-u, -bru), [key] a city on the SW coast of California: Spanish mission. 74,542. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Santa Anna Santa Barbara Islands Related Content Daily Word Quiz: nefarious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language