/ Dictionary / Index S Santayana: Meaning and Definition of Find definitions for: San•ta•ya•na Pronunciation: (san"tē-an'u -ä'nu Sp. sän"tä-yä'nä), [key] 1863–1952, Spanish philosopher and writer in the U.S.; in Europe after 1912. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Santa Tecla Santee Related Content Daily Word Quiz: eccentric Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language