/ Dictionary / Index S Santiago de Cuba: Meaning and Definition of Find definitions for: Santia'go de Cu'ba Pronunciation: (du ky'bu Sp. &thslashe k'vä), [key] a seaport in SE Cuba: naval battle 1898. 277,600. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Santiago Santiago del Estero Related Content Daily Word Quiz: loathe Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language